On Cycle Support Guide: Why It’s Crucial & 3 Key ingredients

Protecting your body during a cycle with steroids, prohormones, or even SARMs is essential. When you're on a cycle of one of the above, your body and organs can be in danger.

This is why it's crucial to use an on cycle support to protect you. If you don't use it, you are putting yourself at risk and could end up having severe adverse effects.

There are many users out there who don't understand why it's crucial to use it. In this cycle support guide, we're going to tell you why, how to use it, and which product offers the most protection.

On cycle support supplements help protect your organs during a cycle. In particular, they help protect the liver, kidneys, and heart. 

Performance enhancers such as anabolic-androgenic steroids can harm the liver and kidneys (1). They can also increase one's blood pressure (2). 

For your body to get the effects of these AAS, they pass through the liver. During this process, they can damage the liver because they're hepatoxic (3). 

You're obviously going to want to prevent this from happening, and that is where cycle support comes to help.

On Cycle Support guide

In these support products, you'll often find high-quality ingredients that can help combat these adverse effects. One of those ingredients that could help you with protection is Milk thistle (4).

It's crucial to use cycle support the entire cycle – from start to finish. I'll show you the best-formulated product that will help keep you protected.

The Best On Cycle Support Ingredients

There's only several on cycle support ingredients that could work when it comes to protecting the organs. That means you should get a supplement that contains the ingredients below.

Allow us to show you some of the most potent ingredients.


TUDCA, short for Tauroursodeoxycholic acid, is an excellent compound to use on cycle. It naturally occurs in the body, but you need to get it through supplementation for the benefits.

TUDCA has shown to help reduce liver enzymes and might have regeneration abilities (5).

It's by far one of the most promising ingredients for cycle support products. Make sure the product you are getting includes this compound as it's the strongest one.

2. Milk Thistle

Milk Thistle, also known as Silymarin, is another highly effective ingredient that could offer protection when on a cycle. It's been around for centuries as a herbal remedy.

It is said to have hepatoprotective effects, precisely what you need when running performance enhancers (6). It also has antioxidant effects that could have other health benefits.

Milk Thistle Cycle Support Ingredients

Therefore, we find it to be a critical ingredient that must be included in liver cycle support products.

3. N-Acetyl-Cysteine

 N-Acetyl-Cysteine (NAC) is a metabolite of L-Cysteine. This compound is beneficial because it has antioxidant and anti-inflammatory effects (7).

It is also useful for protecting the liver and kidneys from potential damage (8). Since steroids, prohormones, and SARMs can damage the liver; it's crucial to prevent this by taking these kinds of ingredients.

I've shown you three of the best on cycle support ingredients. They can all offer some form of protection one way or the other.

This is why it's essential to get yourself a product that contains the above ingredients. I'll show you which product is the best, let's go.

The Best On Cycle Support Supplement

With a simple search, you will find that there are a lot of cycle support products. But the truth is, most of them are poorly formulated and missing key ingredients.

I use one product for all my cycles that I feel is appropriately formulated with the right ingredients.

I'm talking about Defend by Huge Nutrition.

Cycle support supplement

It's the most stacked cycle support for steroids and other performance enhancers you will find. Each serving is four capsules, which means you're getting double the amount of ingredients compared to other products out there.

And because it's got so many high-quality ingredients at the correct dosages, it's great for protecting the organs.

You can get Defend (one month's supply) from the official site for just $49.95. It's a fair price considering you are getting a loaded supplement with 4-capsule serving size.

Do You Really Need Liver Support On Cycle?

In my opinion, every cycle with performance-enhancers requires a liver cycle support supplement.

It's between 50 to 100 bucks to use cycle support for the duration of your entire cycle. 

If you don't have that money for a crucial product like a liver cycle support, maybe you shouldn't be running a cycle in the first place.

In my opinion, it's definitely not a product you should cheap out on. At the end of the day, it's better to be safe than sorry.

If you're going to experience complications with the liver or kidneys, which is a serious possibility, you will regret not having used cycle support.

Also make sure to add in a post cycle therapy supplement like Rebirth

When To Take Cycle Support Supplements

The day you begin your run, that's when you start taking a cycle support supplement. If your cycle lasts for 8 weeks, you also run it alongside for 8 weeks.

Let's say you go with Defend, for example. The product's serving size is four capsules, and you have to take those capsules every day with a meal.

I take my dosage the first thing in the morning with my breakfast. You can take it a different time as it comes down to personal preference, as long as you don't skip a dosage.

The Bottom Line

We've shown you why on cycle support supplements are essential. They help protect your organs – you'll need those to be healthy for the rest of your life.

Those of you that want my advice, go with Defend by Huge Nutrition. It's an incredibly stacked product with a fair price, and use it for all my cycles.

Whichever product you decide to go with, make sure it contains scientifically backed ingredients such as TUDCA and Milk Thistle. They're the crucial compounds that will help massively.

This goes for every supplement, even pre-workout supplements. Check the label before buying it.

If you have tips on maintaining healthy lipids or blood pressure while running performance enhancers, share them in the comments.

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Kyle is passionate about bodybuilding and fitness. He has been training for over two decades and has trained and coached many people in the past. Kyle shares his experience on various supplements, health, and bodybuilding topics. He is a certified health coach and is the CEO of SupplementsReviewer.